The Omega-1 Nanite is a device that features in Generator Rex.
The Omega-1 Nanite or Control Nanite was a type of nanotechnology that was developed as a result of the Nanite Project. It was part of the human-to-machine theory that was espoused by the scientists of the project who believed a human host was needed to control the nanites. It was injected into the body of Rex Salazar by Gabriel Rylander thus providing him control over the nanites in his body. Fellow project scientist Van Kleiss was after the Omega-1 Nanite for his own purposes.
This large silver nanite had the ability to control active nanites within the hosts body.